This article aims to elucidate Mpox, a zoonosis that threatens the African and World continents, where The World Health Organization must take preventive measures to mitigate the viral advances of Mpox, in the search to deal with any viral disease, it is evident that people are aware of taking measures, prevention campaigns and awareness must be carried out among people, discussion of results, the large number of cases become evident at every moment and reduce cases in children and older adults as well as vulnerable people. The origin of the monkeypox disease, or Mpox as it is known today, was discovered in Europe in laboratory monkeys in 1958, and for the first time in humans in 1970, in a child in the Democratic Republic of the Congo (DRC), and since then thousands of endemic cases of the disease have been reported in a resurgence of the disease. In much of the zoonosis, its specific origin is also unknown with precision regarding epidemic outbreaks, through vaccination from 1980 onwards its advances were mitigated, where the vaccine generated immunity against the virus, so the spread was generated by international travel and the vaccine was a means to reduce its progression. The current epidemic outbreak, its transmission route is from person to person or by physical contact, is high risk; in infected people outside the African continent, viral transmission is atypical.

Keywords: mpox, zoonosis, viral disease

Over time, human beings have been overwhelmed by countless viruses and diseases that affect their body, violating their antibody system, all of which harms them in the development of their activities. In addition, man has transformed into a knowing being and invented vaccines against such zoonoses. It is clear that the most recent pandemic, Covid-19, this new viral disease, Mpox, has given advances in its viral action on the African continent. Now, the World Health Organization (WHO) must take measures to prevent a pandemic in the world.¹

Now, the World Health Organization (WHO) is the international organization that is constantly surveillance of viral emergencies and the importance of the health of both low-income and vulnerable people according to the director of the WHO, August 14, 2024 (WHO) - The Director-General of the WHO, Dr. Tedros Adhanom Ghebreyesus, has determined that the resurgence of monkeypox (mpox) in the Democratic Republic of the Congo and in a growing number of African countries constitutes a public health emergency of international concern (ESPII) in accordance with the International Health Regulations (2005).¹

(Figure 1)

Figure 1 Mpox vaccine.

Faced with this reality, each organization or public health ministry in each country working in conjunction with the World Health Organization, working as a team to consciously mitigate the Mpox outbreak in Africa, and prevent its viral advances in the world. Several cases of VSV infection with anogenital manifestations have been documented, considering men who have sexual practices with men as high-risk groups.²

In other words, monkeypox is an emerging zoonotic disease recognized as the infection Orthopoxvirus most important in humans after the eradication of smallpox1. Monkeypox virus (MSV) was first identified in monkey colonies in Copenhagen, Denmark, in 19582.³ All of this makes us reflect on such effects on human beings due to these infections.

Declaring PHEIC, Dr Tedros said: "The emergence of a new clade of Mpox virus, its rapid spread in the east of the Democratic Republic of Congo and the reporting of cases in several neighboring countries is very worrying news. In addition to the outbreaks of other clades of Mpox virus in the Democratic Republic of Congo and other African countries, it is clear that a coordinated international response is needed to stop these outbreaks and save lives."³ Health measures are necessary publishes in African countries, to save lives in these social and scientific aspects.

The Chairman of the Committee, Professor Dimie Ogoina, said: "The current resurgence of Mpox in different areas of Africa, together with the spread of a new sexually transmissible strain of the virus causing the disease, constitutes an emergency, not only for Africa, but for the entire planet. Mpox did not receive the attention it deserved in Africa, where it originated, and later caused a global outbreak in 2022. It is time to act decisively to prevent history from repeating itself."¹

Now, what to do about this zoonosis that is harming the African continent? It is necessary that public health organizations such as the WHO make sound decisions to avoid risks that later reflect damage to society as Covid-19 did, becoming a pandemic. Developed countries such as the United States of America, China, Russia, the United Kingdom, Germany and France contribute as much as possible to this continent so battered by various diseases, as is happening with the MPOX virus (Figure 2).

Figure 2 Strain and person contagion.

The need that arises to counteract all aspects of avoiding a pandemic corresponds to taking sanitary measures that are taken efficiently by society, to avoid contagion and thus mitigate the effects of the spread of the virus as occurred with the coronavirus, with social isolation with necessary public health measures taking into account each of these measures without refusing, to avoid a massive action of contagion, of MPOX, monkeypox, advances in the African continent, large health organizations must think and rethink about it, we have had a great mirror with Covid 19.

Continuing with the opinion, not only organizations must think, but also the society that is closest to the contagion and comes into contact with infected people who did not take sanitary measures. It is vitally important to rethink with social awareness, thus avoiding the whole amalgam of infections that are foreseen in the future if they are not mitigated efficiently and quickly.

We must all act with certainty about the spread of the simian virus, if we do not listen to each other as happened with the Covid 19 pandemic, we will find ourselves in a shipwreck of doubts, the need arises to visualize the path towards finding ourselves as knowing beings thinking about children and older adults with this virus, if we continue to row towards a harmful cause of different pandemics in the world if we do not control the advance with vaccines, we will be ridiculous in the face of this with so much scientific knowledge and knowledge is useless if we do not listen to each other we will head towards the gorge with the possibility of being a threat to human existence (Figure 3).

Figure 3 Infected person.

We let all the viral effects of these diseases spread unchecked. What happens to humans? As we move toward a surrounding future, with technological advances and artificial intelligence, viruses spread in such a way. With so many tools at our disposal to find vaccines and different scientific means, we are left on the sidelines without quick solutions to prevent the spread of the MPOX virus worldwide.

Monkeypox, or Mpox, is a zoonosis that is advancing as a virus of concern to the World Health Organization (WHO); Since the Covid-19 pandemic, humanity has faced a series of viruses that threaten humans, including Omicrom, a mutation of Covid. In the face of these viruses, we must become aware and be conscious subjects to mitigate their spread. Several factors may contribute to the emergence of Mpox as a threat after smallpox. It is evident that overcoming the challenges presented by these viral diseases, and Mpox is advancing recklessly, silently before our eyes, as Maturana warns. "Without a pandemic or with it, we will go straight to extinction."⁴

Mpox is a viral disease with pandemic potential resulting from the mutation of viruses similar to variants such as Omicron and all the others that caused great havoc in world society. The Mpox outbreak in the Democratic Republic of the Congo shows signs of following a similar trajectory to the recent regional spread. As of December 2024, cases have been reported in travelers from numerous countries, including the United States, Canada, and the United Kingdom. Therefore, the good doctor anticipates the crisis, this must make them aware and take humane measures in people, where. The treated individual is perceived as a patient, but ignored as a person. He is isolated from his human environment.⁵

All viral diseases distance us from the social issue of becoming human and relating to each other, but when we become aware of isolating ourselves, it makes us people aware of taking sanitary measures, due to the increase in cases of Mpox. Exposures are multifactorial, from an increase in the absolute number of people living in the Mpox endemic countries of West and Central Africa, this is how humanity must learn to live and perceive the damage caused by viruses and their effects, such as Mpox, in the African continent, exacerbates the effects of the virus. Our science and our medicine have isolated us from the world as if we were strangers to it.⁵

MPOX in the modern era is also influenced by new complexities, including underlying medical conditions. The recent rise in MPOX introduces another factor of concern: the risk of new genomic mutations. To control such mutations and protect against a potential future pandemic, minimizing the spread of MPOX is essential; this includes incorporating MPOX prevention strategies for at-risk populations into healthcare.

The large number of cases that occur in the Congo, Zimbabwe, and many other countries in the region, as has been happening. Last year, reported cases increased significantly, and the number of cases reported so far this year has already exceeded last year's total, with more than 15,600 cases and 537 deaths between 2023 and 2024. Although cases have decreased, we are still on alert to avoid further outbreaks, as cases have been found in Europe, America, Asia and Oceania. It is a reality that the World Health Organization continues its fight to eradicate viral diseases. On the different continents of the world.

Finally, viruses spread because we do not listen consciously to each other due to contagion from social contact with people infected with monkeypox. It is clear that public health agencies carry out propaganda and advertising to avoid contagion and we do not pay attention to the events that occur worldwide. Man is the only animal that stumbles twice on the same stone, does not learn from its mistakes, or perhaps because it does not observe what happens in the social panorama.

Given the evidence regarding MPOX and its growth as a viral disease, which has had a major impact on global society and is a source of great concern to health organizations such as the World Health Organization (WHO) and the Pan American Health Organization (PAHO), the African continent is experiencing many adversities related to viral diseases that are causing global concern. Looking ahead, the best way to control MPOX is through vaccination.

If large developing countries were to invest in humanitarian aid for this continent so devastated by viruses, countries like the Democratic Republic of the Congo, Nigeria, and others would also be able to do so. Viruses like Ebola exist, where many people die from this disease. Therefore, it is necessary to counteract viruses early, but how to do so by taking precautions and educating society.

Mpox is a very broad and complex topic to understand, as long as human beings are more humane and understand the realities we live in today. We seek to understand a complex reality with vaccines that develop antibodies in individuals, so we can live in a better world without viruses or bacteria that harm human beings.

None.

The author declares there is no conflict of interest.

None.

1. World Health Organization (WHO). Emergency of public health due to the Mpox outbreak. 2024.
2. Alvarez-Guacichulca J. Monkeypox: a narrative review of pathophysiology. Chilean Magazine Infectol Orci-pathogenesis. 2023.
3. World Health Organization (WHO). Public health emergency due to the Mpox outbreak. 2024.
4. Maturana. 2020.
5. Morín E. The way to the future of humanity. Spain: Paidos, 2011;p. 165.