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Research Article Volume 18 Issue 4
Hearts under fire: acute myocardial infarction care during Sudan’s humanitarian crisis
Abdelmuniem Ahmed, Najla Mohammedali, Ibrahim Elkhidir, Israa Mohamed, Hibatallah Ahmed, Sobul Ali, Osman Abdelhamed, Mohamed O. Ahmed, Ashraf Ahmed
Received: November 07, 2025 | Published: December 18, 2025
Citation: Ahmed A, Mohammedali N, Elkhidir I, et al. Hearts under fire: acute myocardial infarction care during Sudan’s humanitarian crisis. J Cardiol Curr Res. 2025;18(4):211-215. DOI: 10.15406/jccr.2025.18.00634
Abstract
Background: Acute myocardial infarction (AMI) poses a significant health threat globally, particularly in low-middle income countries (LMICs). Amidst challenges such as armed conflict, percutaneous coronary interventions (PCI) may not always be feasible, necessitating reliance on thrombolysis therapy as a reperfusion strategy. This study aims to evaluate the short-term outcomes of thrombolysis in patients with ST-segment elevated MI during the Sudanese humanitarian crisis. Methods: A retrospective cohort study was conducted enrolling patients admitted to the Medani Heart Center during the Sudanese conflict. Data encompassing demographic details, laboratory findings, risk factors, echocardiographic assessments, and outcomes. Logistic regression analyses were employed to discern predictors of failed thrombolysis, adverse events, and mortality. Results: Of the 72 patients, 69.4% were male, with a mean age of 59.9 years. Most presented with anterior STEMI, and the mean time from symptom onset to presentation was 4.8 hours. Notably, failed thrombolysis occurred in 49% of cases, with predictors including decreased high-density lipoprotein cholesterol levels, ejection fraction (EF) less than 50%, and regional wall motion abnormalities (RWMA). Adverse events were observed in 66.5% of cases, primarily heart failure (47.2%). The mortality rate stood at 9.7%, with predictors being reduced EF and RWMA. Conclusion: Thrombolysis has a comparable outcome as a primary modality of coronary reperfusion in resource-limited practice. Failed thrombolysis significantly increased the risk of mortality, providing crucial insights into the application of thrombolytic therapy in STEMI within low-middle-income countries.
Keywords: Hearts under fire: acute myocardial infarction care during Sudan’s humanitarian crisis
©2025 Ahmed, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.