Research Article Volume 8 Issue 1
Received: January 07, 2020 | Published: January 22, 2020
Citation: Vetvicka V, Fernandez-Botran R. Non-specific immunostimulatory effects of transfer factor. Int Clin Pathol J. 2020;8(1):1-5. DOI: 10.15406/icpjl.2020.08.00197
The focus of this study was to confirm the hypothesis that food supplementation with colostrum- and egg-derived transfer factor can positively influence immune reaction. Our results found that phagocytosis, proliferation of spleen cells, NK cell cytotoxicity, IL-2 and IFN-γ production were significantly stimulated by feeding with transfer factor. Production of antibodies and IL-4, IL-5, IL-10 and TNF-α and the cellular composition of spleen was not affected. From our data we conclude that this type of transfer factor affects both cellular and humoral branch of immune reactions.
Keywords: NK cell cytotoxicity, spleen cells, IL-2 and IFN-?
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